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Sep 18, 2024

Mental Health

Kyzatrex: A More Convenient Testosterone Replacement

Approved in 2022, KYZATREX brings a novel approach to testosterone replacement therapy that's distinguished from traditional methods. Unlike the conventional treatments that rely on patches, gels, or injections, KYZATREX is administered orally, providing a less invasive option that many patients prefer.

KYZATREX is designed to mimic the body’s natural testosterone production rhythm, avoiding the "peaks" and "valleys" typically seen with injectable testosterone. This results in a more stable hormonal balance that closely aligns with natural testosterone cycles.

In clinical studies, KYZATREX has demonstrated significant effectiveness. A 6-month study showed that 88% of participants reached normal testosterone levels within the first 90 days, with this figure rising to 96% over the full course of the study. This level of efficacy underscores KYZATREX's potential as a transformative option in hormone replacement therapy.

KYZATREX is not indicated for use in women and should not be used in children, as it may impact bone growth.

Dosage and Administration

KYZATREX is available in three strengths: 100 mg, 150 mg, and 200 mg. The specific dosage will depend on the individual's medical condition, testosterone levels, and response to treatment.

KYZATREX should be taken orally, twice daily, with food. Taking KYZATREX with meals, particularly those containing fats, can improve the absorption of testosterone undecanoate through the lymphatic system, as dietary fats help facilitate its uptake.

Alcohol Interaction

One of the conveniences of KYZATREX is that there are no known interactions between the medication and alcohol. Therefore, patients can consume alcoholic beverages while on this treatment without worrying about direct interactions affecting the efficacy or safety of the medication.

How KYZATREX Works

KYZATREX functions by supplementing the missing testosterone, aiming to restore these levels to the normal range.

Improved Absorption

Traditional oral testosterone therapies have faced challenges with absorption and bioavailability due to the liver's role in metabolizing the hormone. Typically, oral testosterone is transported directly to the liver, where the hormone is significantly metabolized (broken down) before it can have effects in the body. This often reduces the efficacy of the hormone and can lead to liver stress or damage.

The uniqueness of KYZATREX lies in its use of testosterone undecanoate, a fatty acid ester that enables the hormone to be absorbed more effectively through the intestinal lymphatic system rather than the liver. This improves absorption and reduces the potential for liver toxicity.

Steady Testosterone Levels

KYZATREX is specifically designed to mimic the body’s natural testosterone rhythms, providing a more stable and sustained hormone level. This avoids the peaks and valleys commonly associated with injectable testosterone, which can lead to mood swings and fluctuating energy levels.

Safer for Long-term Use

Since KYZATREX doesn’t overload the liver, it’s generally safer for long-term use compared to other forms that might pose risks to liver health. This is particularly important for individuals who need ongoing treatment to maintain their testosterone levels.

Side Effects

The most common side effect of KYZATREX is an increase in blood pressure, which could increase the risk of cardiovascular events such as heart attacks or strokes. It's important to inform your healthcare provider about any existing risk factors before starting this medication. They will monitor your blood pressure regularly during treatment to ensure safety. The potential benefits of KYZATREX should be carefully weighed against any possible health risks.

Additional side effects of KYZATREX may include:

  • Headache
  • Increased hemoglobin
  • Joint pain
  • Diarrhea
  • Anxiety

Unlike other testosterone therapies, KYZATREX does not cause erythrocytosis—an increase in red blood cells that can lead to severe complications. This absence of erythrocytosis is a significant advantage of using KYZATREX.

KYZATREX Through Marley Drug

KYZATREX is available through Marley Drug, thanks to our partnership with Marius Pharmaceuticals. We offer a 120-capsule supply of KYZATREX for $159, regardless of dosage. This offer is available directly through Marley Drug and includes:

  • No insurance needed
  • Available to all patients holding a valid prescription
  • Statewide shipping available*

*Please note KYZATREX is a Schedule 3 controlled substance and misused can lead to physical/psychological dependence or addition.



References:

  1. KYZATREX (testosterone undecanoate) capsules, for oral use. Food and Drug Administration. (1953; revised: 07/2022). Retrieved February 18, 2024, from https://www.accessdata.fda.gov
  2. Be The Hero: KyzatrexTM oral testosterone undecanoate – KYZATREXTM. KYZATREX. (n.d.). Retrieved February 18, 2024, from https://www.kyzatrex.com/

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