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Lower Your Heart Disease Risk by 31% with LODOCO®

  • $99/month with free shipping
  • First anti-inflammatory cardioprotective treatment
  • No insurance required
  • Available to all patient with a valid prescription

Protect Your Heart: Be Proactive with LODOCO

In 2023, LODOCO (low-dose colchicine) became the first approved anti-inflammatory treatment that lowers the risk of cardiac events. It's designed for those who already have heart disease or are at a high risk of suffering a heart attack.

31% Lower Risk: A Breakthrough in Heart Health

Clinical trials have demonstrated that LODOCO can reduce the risk of heart issues by 31% compared to a placebo. This benefit comes from adding it to your usual heart care routine, which may include high-intensity statins.

Save on LODOCO through Marley Drug

Through Marley Drug you can access LODOCO for $99/month, thanks to an agreement with the manufacturer AGEPHA Pharma.

The manufacturer and Marley Drug share the goal of providing broader access to drugs at a low out of pocket cost. Through this agreement we can offer this medication at a much lower price than other brand medications by bypassing wholesalers and insurance middlemen (which contribute to the high cost of medications).

Consider discussing LODOCO with your physician during your next appointment. To facilitate this conversation, download and bring the information sheet to your visit.

Download Info Sheet

How LODOCO Works

Inflammation and Cardiovascular Disease

Inflammation and Cardiovascular Disease

Low-dose colchicine (LODOCO) works to reduce inflammation in a unique way that benefits the heart and blood vessels.

Colchicine is a medication that has been used for a long time, mostly to treat gout by reducing inflammation and pain. When it comes to heart disease, inflammation plays a significant role in the development and progression of atherosclerosis, which is the buildup of plaques in the arteries that can lead to heart attacks and strokes.

At low doses, colchicine works by calming the body's response to inflammation. It does this by affecting white blood cells, which play a big role in the development of artery-blocking plaques. By interfering with certain parts inside these cells, LODOCO keeps them from becoming overly active and causing inflammation. It also lowers the levels of certain inflammation-causing substances in the body and affects various cell activities that lead to the buildup of plaques in the arteries.

By damping down the inflammation in this manner, low-dose colchicine helps to reduce the risk of cardiovascular events, such as heart attacks and strokes, particularly in people who have established cardiovascular disease or are at high risk for heart disease. This anti-inflammatory effect, with a focus on the cardiovascular system, is what makes LODOCO an innovative treatment option for reducing the risk of cardiac events.

LODOCO has shown to reduce CRP levels. CRP stands for C-reactive protein and is produced by the liver in response to inflammation, so an elevated CRP level suggests that there is inflammation occurring somewhere in the body. While we know LODOCO can help prevent serious heart problems, the exact way it achieves this protection is still being studied.

How to Get LODOCO

Order Euthyrox online
Transfer Prescription

Transferring your prescription to Marley Drug is easy. Fill out a simple form, and we will take it from there. All orders are confirmed with a phone call before shipping.

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Order EUTHYROX online
Shop Online

Order LODOCO on our site. During checkout you're given a choice for the prescription delivery. You can ask your physician to send the prescription to Marley Drug, or we can contact them on your behalf. Either way we do our best to make the process easy for you.


Hear from our Customers

I really love Marley’s quick responses and the fact that I can purchase a 6 month supply rather than running to the drugstore every 30/90 days. The staff is wonderful, helpful and knowledgeable. I love ...
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Patty S.
The Wholesale Price List made my prescription easy to afford, I was about to cancel my prescription because my monthly cost with insurance was almost $150! Now I can get a 6-month supply for only $37 ...
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Mark T.
Great Pharmacy. If your insurance company will not pay, you can get medications. A lot cheaper.
Shirley F.
As soon as my doctor submitted the prescription, I was contacted by Terri, who explained the process and set up delivery to my home. It could not have been easier!
Amy W.
Stock photos are used to represent actual testimonials of Marley Drug customers.

Have medication questions about LODOCO?
Talk with a pharmacist today.

Call us for a free pharmacy consult.


Common Questions about LODOCO

Data informed by:

1 Nidorf SM, Fiolet ATL, Mosterd A, et al. Colchicine in Patients with Chronic Coronary Disease. N Engl J Med. 2020;383(19):1838-1847. doi:10.1056/NEJMoa2021372