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Metformin Not Enough to Manage A1C? What's Next?

When metformin falls short in controlling your A1C levels, it's time to consider combination therapy. While the high cost of additional medication can be a barrier for many Americans, BRENZAVVY offers a powerful and affordable solution at just $59.95.

37.3 million Americans struggle with Type 2 Diabetes—when not managed properly it can lead to complications such as heart disease, organ damage and nerve damage. Management often requires a multifaceted approach, combining lifestyle changes with medications when necessary. Metformin is typically the first medication your healthcare provider will recommend.

When Metformin isn’t enough to lower your glucose to healthy levels, your doctor may suggest combination therapy.

There are now several medication classes available, each with its own history and unique benefits. With metformin being the gold-standard in diabetes management, most have also been studied with metformin to show additional benefits in managing blood glucose levels.

The problem with these new medications (JARDIANCE, FARXIGA, INVOKANA) is with access—most cost upwards of $500/month. That was until recently, when BRENZAVVY (bexagliflozin), an SGLT-2 inhibitor, became available in the U.S. in 2023.

Through a partnership with the manufacturers of BRENZAVVY, we are excited to offer this new medication for just $59.95/month—90% less than the cost of other branded medications from the same drug class.

Why Choose BRENZAVVY (bexagliflozin)?

Proven Effectiveness
  • Enhanced Results with Metformin: When combined with metformin, BRENZAVVY has shown superior A1C reductions compared to metformin alone.
  • Better Blood Sugar Control: BRENZAVVY works by helping your kidneys remove excess glucose from your bloodstream, significantly improving blood sugar levels.

Cost-Effective Solution—90% Less than other Oral Options
  • Affordable Therapy: Our pharmacy offers BRENZAVVY at a much lower cost than other branded oral medications, making it a budget-friendly option.

Convenient and Easy to Use
  • Simple Oral Medication: BRENZAVVY is easy to take, ensuring you stay on track with your treatment regimen.

Additional Health Benefits
  • Weight Loss: BRENZAVVY may help promote weight loss, an important factor in diabetes management.
  • Lower Blood Pressure: It also offers benefits for your cardiovascular health by helping to lower blood pressure

How Does BRENZAVVY Work?

BRENZAVVY (bexagliflozin) helps your body manage blood sugar levels by:

  • Increasing the amount of glucose excreted through urine
  • Reducing the amount of glucose your kidneys reabsorb
  • Complementing the action of metformin for enhanced blood sugar control


Order online or over the phone

If you run into issues, just give us a call at 800-810-7790.

We will verify your prescription

We can contact your doctor for the prescription.

We will ship it to your home

Ship through USPS First Class Mail to all 50 states. Our average delivery time is 2 days.

Hear from our Customers

I really love Marley’s quick responses and the fact that I can purchase a 6 month supply rather than running to the drugstore every 30/90 days. The staff is wonderful, helpful and knowledgeable. I love ...
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Patty S.
The Wholesale Price List made my prescription easy to afford, I was about to cancel my prescription because my monthly cost with insurance was almost $150! Now I can get a 6-month supply for only $37 ...
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Mark T.
Check out this mail in pharmacy. My cardiologist referred me to them for best price on cholesterol lowering med. I found them to be helpful, professional and provide prompt service.
Theresa S.
As soon as my doctor submitted the prescription, I was contacted by Terri, who explained the process and set up delivery to my home. It could not have been easier!
Amy W.
Stock photos are used to represent actual testimonials of Marley Drug customers.

Have medication questions?
Talk with a pharmacist today.

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Most commonly asked questions about BRENZAVVY

Clinical Studies with Brenzavvy

Brenzavvy has been studied as a monotherapy (Study #1 below), and in combination with metformin in adults with type 2 diabetes (Study 2,3 and 4 below). It has also been studies in adults with type 2 diabetes who also have moderate renal impairment (Study 5 below) and in adults with type 2 diabetes and established cardiovascular disease (Study 6 below).

The following information is taken from the Brenzavvy Prescribing Information. The Prescribing Information is the Food and Drug Administration (FDA)'s primary tool for communicating a summary of the essential scientific information needed for the safe and effective use of a prescription drug to healthcare providers. We have done our best to digest this information and provide it in a format that is understandable for all audiences. For any clarification on the information below please refer to the Brenzavvy Prescribing Information at or talk with your healthcare provider or one of our pharmacists.