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Apr 4, 2024


Fatigue, dry skin, constipation, weight gain, depression, and a low heart rate are all symptoms of having low thyroid hormone levels. This is a medical condition called hypothyroidism (hypo meaning ‘low’). A simple blood test can help you determine if your thyroid levels are in the normal range.

Luckily, hypothyroidism is quite treatable. Thyroid hormone replacement therapies are the cornerstone in managing hypothyroidism.

Levothyroxine as Thyroid Hormone Replacement

Levothyroxine is a first-line treatment option for managing low thyroid levels. It works by supplementing the body's natural hormone levels with synthetic thyroxine hormone. This helps to alleviate the symptoms of hypothyroidism, ensuring patients can maintain normal metabolic function.

Importantly, levothyroxine has a very narrow therapeutic window. This means that small differences in the dose of the medication can greatly affects the potency of the medication. That's why patients often go through a trial-and-error process, tweaking their doses until they find the right balance.

Levothyroxine comes in various strengths, ranging from 25 mcg to 300 mcg tablets. And because consistency is key, it's recommended to stick with the same brand to avoid any slight variations.

Learn more about levothyroxine uses, dosages and side-effects


Two of the most well-known brands of levothyroxine are EUTHYROX and SYNTHROID.

EUTHYROX has gained popularity worldwide and recently became available in the U.S. What sets it apart is its blister packaging, which we'll dive into shortly.

SYNTHROID, on the other hand, has been around since 2004 and comes in traditional bottles. Despite the availability of generic versions, SYNTHROID remains widely used in the U.S.

The FDA considers EUTHYROX and SYNTHROID to be bioequivalent, meaning they should work similarly and have comparable safety profiles. But their packaging and cost differ.

Learn more about different treatment options for hypothyroidism

EUTHYROX: Blister Package for Enhanced Protection

EUTHYROX is known for its blister packaging. This unique feature helps protect the medication from light, oxygen, and moisture, which can degrade its effectiveness over time. Since levothyroxine's potency is crucial, this packaging ensures each dose remains potent until you take it.


EUTHYROX tends to be more affordable, especially if you're purchasing it from select pharmacies like Marley Drug. Thanks to a partnership with Provell Pharmaceuticals, Marley Drug offers EUTHYROX at a fraction of the cost of SYNTHROID—as low as $7 per month for a year's supply.

SYNTHROID, on the other hand, can be pricier, often ranging from $170 to $190 per month. While there are cost-saving programs available, like the SYNTHROID Delivers Program, it still may not beat the affordability of EUTHYROX.

Active Ingredient Levothyroxine Sodium Levothyroxine Sodium
Inactive Ingredients Citric acid anhydrous, croscarmellose sodium, gelatin, magnesium stearate, maize starch, mannitol Acacia, confectioner’s sugar, lactose, magnesium stearate, povidone, talc. Some strengths also include color additives
Strengths From 25 mcg to 200 mcg From 25 mcg to 300 mcg
Packaging Blister package Bottle
Interactions Antidepressants, Warfarin, Diabetes medications, Iron supplements, etc. Taken by mouth, once a day, with or without food
Retail Cost $7/month when ordering a 12-month supply $150-$170/month

EUTHYROX through Marley Drug

Marley Drug offers EUTHYROX for $84/year thanks to an agreement with Provell Pharmaceuticals. This partnership allows us to eliminate supply chain middlemen like wholesalers and insurance companies, which contribute to the high cost of medications.

There is no pre-approval requirements, or insurance hoops to jump through to access EUTHYROX. As long as we have a valid prescription from your healthcare provider we can fill your prescription for as low as $7 per month.

Once we receive the prescription from your healthcare provider we will call you to confirm your order, shipping address and payment details. We will then ship you the medication by USPS First Class Mail and the medication should arrive within 2-3 business days.

Learn more about accessing EUTHYROX through Marley Drug