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Apr 28, 2023

Blood Pressure


Triamterene (Dyrenium)

What is it?

Triamterene is used for managing high blood pressure and edema (fluid build-up).

Triamterene is a diuretic which is a drug class that acts on the kidneys to increase urine production, flushing out excess water and salt.

Triamterene medication is also available in combination with hydrochlorothiazide (HCTZ), another diuretic (brand: Dyazide). This combination medication is effective for those who are not responsive to a single medication to treat their high blood pressure or edema.

Triamterene Dosage

Typically, the dosage to treat either high blood pressure or edema is 100 mg of triamterene two times per day.

If you take the combination triamterene with HCTZ, the dose is typically one or two capsules per day. Each capsule contains triamterene 37.5 mg and hydrochlorothiazide 25 mg.

Pediatric use is not recommended as there have not been studies to assess safety and efficacy of the medication in children.

Triamterene Side Effects

Common Side Effects

These side effects are mild and usually short-lived as the body adjusts to the medication. If any of the following side effect become bothersome or last more than a few days speak to your pharmacist or healthcare provider:

  • Dizziness
  • Stomach pain
  • Headaches
  • Diarrhea
  • Fatigue
Serious Side Effects

These side effects are rare but could indicate serious health complications. Speak to your healthcare provider immediately if you experience any of the following:

  • Dehydration: decrease in urine production, increased thirst, confusion, fast/irregular heartbeats, lightheadedness/fainting
  • Painful urination or blood in urine
  • Yellowing of eyes/skin
  • Joint pain
  • Easy bruising/bleeding
  • Allergic reaction: rash/itching, swelling of face/throat, trouble breathing


Some medications are known to affect the way triamterene works or increase your chance of side effects. Speak to your healthcare provider about any current medications and new medications you may begin taking while on triamterene.

Some medications that may interact with triamterene are:

  • Medications that increase potassium (e.g., potassium supplements, cyclosporine, birth control with drospirenone, lithium)
  • Other medications that treat high blood pressure or have the side effect of lowering blood pressure
  • NSAIDs (e.g., ibuprofen, naproxen)
Triamterene and Alcohol

Alcohol can interact with triamterene to increase drowsiness and affect reflexes and judgement. Alcohol also affects your blood pressure and heavy drinking can lead to heightened blood pressure.

If you choose to drink, be sure to not exceed the daily recommended limit of 1 unit/day for women and 2 units/day for men.

Triamterene Cost

The average retail triamterene (Dyrenium) price is $342.66 for 30 capsules of 100 mg.
For triamterene with hydrochlorothiazide (Dyazide), the average price is $11.84/30 capsules.

Get Triamterene Online Less at Marley Drug

Marley Drug offers triamterene/HCTZ through our Wholesale Price List which offers over one hundred medications at consistently affordable prices. You can get triamterene/HCTZ for as little as $5.83/month.

We also offer free shipping to all 50 states, saving you both money and time on your medications by cutting out your monthly pharmacy trips.

Questions or concerns? Call us today at +1 800-810-7790 and our pharmacy team will be happy to assist you.

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