Struggling with Blood Sugar Spikes after Meals?

Get Generic Sitagliptin for $80/month

How Sitagliption Works

Sitagliptin belongs to a class of medications called DPP-4 inhibitors, used to manage blood sugar levels. These medications have a unique way of working: they adjust their activity based on your body's current glucose needs. They work harder to lower blood sugar when levels are high (like after a meal) and have less effect when levels are normal or low, reducing the risk of excessively low blood sugar (hypoglycemia).

Why Does This Matter?

• Sitagliptin primarily works when you need them most, such as after meals when blood sugar tends to spike.
• Because its activity is dependent on blood sugar levels, sitagliptin is less likely to cause hypoglycemia compared to other diabetes medications.

The Science Behind It

To understand how sitagliptin works, it's helpful to know about your body's natural response to food:

1. Incretin Hormones (GLP-1): When you eat, your gut releases hormones called incretins, most notably GLP-1. GLP-1 plays a key role in blood sugar control by:
   • Stimulating the pancreas to release insulin
   • Sending signals to the brain that promote feelings of fullness
2. The Role of DPP-4: DPP-4 enzyme rapidly breaks down GLP-1 in the bloodstream, limiting its action.
3. How Sitagliptin Works: Sitagliptin inhibits the DPP-4 enzyme. By blocking DPP-4, sitagliptin prevents the rapid breakdown of GLP-1. This allows GLP-1 to remain active in the body for a longer period, resulting in:
   • Increased insulin release when blood sugar is high
   • Better blood sugar control, especially after meals
   • Improved feelings of fullness

How Sitagliptin Helps

• Effective: Sitagliptin lowes A1C by 0.7% in those aleady taking metformin. This reduction is significant, as A1C levels reflect long-term blood sugar control, and even a small decrease can improve health outcomes.
• Safe: Sitagliptin is well-tolerated, with a low risk of adverse drug interactions, hypoglycemia (low blood sugar) or gastrointestinal issues, making it a safe option for many patients.
• Affordable: The cost of generic sitagliptin is $80/month which is 80% less than the brand.
• Convenient: Order online and get it delivered to your door.

Who Can Benefit from Sitagliptin?

• Adults with type 2 diabetes whose HbA1c levels are not adequately controlled by metformin alone.
• Adults with type 2 diabetes who experience inconsistent blood glucose levels throughout the day.
• Adults with type 2 diabetes seeking a more affordable treatment option.
• Individuals with high out-of-pocket medication costs, including those who are unemployed, self-employed, or on government programs.

Why Marley Drug

Get Generic Sitagliptin for $80/month

DPP-4 inhibitors have become an important treatment option foir type 2 diabetes. However, the retail cost of these medications often exceed $600 per month, which puts them out of reach for many individuals.

Soon after ZITUIVO (brand sitagliptin) and generic sitagliptin entered the U.S. market in 2023, Marley Drug partnered up with the manufacturer, Zydus, to offer generic version at an affordable cash price to all Americans. This partnership bypasses intermediaries like PBMs and insurance that contributes to high drug cost. With this model we transfer the savings directly to you.

All you need is to send a prescription to Marley Drug.

Need a prescription?

Download Sitagliptin Information to bring to your doctor's appointment.

Managing Blood Sugar Spikes

High blood sugar, especially after meals, can lead to fatigue, mood changes, and long-term health complications like kidney disease, heart disease, and dementia.

Risk of High Blood Sugar

Recurrent spikes in your blood sugar can raise your HbA1c levels, which are known to increase the risk of other health concerns. Keeping these numbers in check can be even more challenging as we ago. Keeping these numbers under control are key to preventing complications of diabetes as we get older.

Reducing after-meal blood sugar spikes can be achieved with medication management and dietary changes.

Lifestyle

We always recommend to try lifestyle changes first before adding on additional medications. Monica, a pharmacist who works with Marley Drug provides tips and strategies to help manage post-medal blood sugar levels.

When Lifestyle Changes Don't Work

The reality is that for many patients lifestyle changes do not work, or are not realistic. That's when it may be time to consider medication solutions, such as sitagliptin, which is discussed above throughout this page.