This class of medications adapt to the body's fluctuating glucose needs. When blood sugar levels are high, these medications work harder to bring them down. When levels are low or within the normal range, they have less effect.
To understand how sitagliptin functions, it’s important to know your body’s natural response to food.
As you digest a meal, your body releases an incretin hormone called GLP-1. This hormone helps lower blood sugar by:
However, GLP-1 is quickly broken down in the bloodstream by the DPP-4 enzyme. Sitagliptin inhibits this enzyme, preventing GLP-1 from degrading too quickly. This means that sitagliptin allows GLP-1 to stay active longer, effectively managing blood sugar levels and maintaining a feeling of fullness.
What makes sitagliptin unique is its ability to adapt to your body’s needs. It works more intensively when blood sugar is high and eases off when levels are normal, reducing the risk of hypoglycemia (excessively low blood sugar). This tailored approach makes sitagliptin a safe and effective option for managing blood sugar.
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Sitagliptin is an FDA approved prescription medication that can help manage Type 2 Diabetes. It works similarly to some brand-name medications, but at a significantly lower cost.
Generic sitagliptin is available for $80/month through Marley Drug.
In clinical studies, sitagliptin has been shown to help lower hemoglobin A1C levels in those already taking metformin by 0.7%.
For those managing Type 2 Diabetes, DPP-4 inhibitors have become an important treatment option. Focusing on the body’s natural ability to regulate glucose levels, this drug class has significantly expanded the therapeutic options, offering a combination of efficacy, safety, and convenience.
However, the retail cost of these popular medications can be steep, often exceeding $600 per month, which puts them out of reach for many individuals.
ZITUIVO (brand sitagliptin) and generic sitagliptin entered the U.S. market in 2023. Marley Drug partnered up with their manufacturer, Zydus, to offer generic sitagliptin at an affordable cash price to all Americans. This partnership bypasses intermediaries like PBMs and insurance that contributes to high drug cost. By bypassing them we transfer the savings directly to you.
Getting generic sitagliptin for $80 per month is straightforward:
Sitagliptin is recommended alongside diet and exercise to enhance blood sugar control in adults with Type 2 Diabetes. It is not suitable for those with Type 1 Diabetes or with a history of pancreatitis.
Download the Sitagliptin info sheet to bring to your next doctor's appointment.
When blood sugar spikes after eating, it can leave you feeling tired, lethargic and moody. Over time, chronic blood sugar issues can put you at risk for conditions like kidney disease, heart disease and even dementia.
The good news? You can take steps to better manage your blood sugar levels, whether through lifestyle changes or medications.
Recurrent spikes in your blood sugar can raise your HbA1c levels, which are known to increase the risk of other health concerns. Keeping these numbers in check can be even more challenging as we ago. Keeping these numbers under control are key to preventing complications of diabetes as we get older.
Reducing after-meal blood sugar spikes can be achieved with medication management and dietary changes.
We'd always recommend to try lifestyle changes first before adding on additional medications. Monica, a pharmacist who works with Marley Drug provides tips and strategies to help manage post-medal blood sugar levels. There are additional articles and resources below.
The reality is that for many patients lifestyle changes do not work, or are not realistic. That's when it may be time to consider medication solutions, such as sitagliptin, which is discussed above throughout this page.
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